Scott spent the entirety of 2018 with Triple–A Round Rock, appearing in 44 contests and pitching to a 5–5 record and 3.26 ERA with 52 strikeouts across innings pitched. He elected free agency following the season on 2 November 2018.
[
]
Scott was called up to the major leagues for the first time on 7 June 2019.[ He made his major-league debut on 8 June, becoming the first South African pitcher in MLB history.] He pitched innings in his debut, against the Los Angeles Angels, allowing three runs on four hits. His first strikeout was against Wilfredo Tovar.
Baltimore Orioles
On 25 June 2019, Scott was claimed off waivers by the Baltimore Orioles. In eight appearances for the Orioles, Scott struggled to an 18.69 ERA with 7 strikeouts in innings of work. He was markedly better with the Triple–A Norfolk Tides, registering a 0.56 ERA with 21 strikeouts across 13 appearances. On 30 October, Scott was removed from the 40-man roster and sent outright to Triple–A Norfolk. He elected free agency on 4 November.
Hiroshima Toyo Carp
On 1 December 2019, Scott signed a one-year contract with the Hiroshima Toyo Carp of Nippon Professional Baseball (NPB). In 2020, Scott struggled to a 15.75 ERA in 7 games for Hiroshima.[ Scott did not appear in a regular season game for the Carp in 2021 and became a free agent after the season.
]
San Diego Padres
On 7 March 2022, Scott signed a minor league contract with the San Diego Padres organization. On 3 July, the Padres selected Scott's contract, adding him to their active roster. In eight appearances for San Diego, he struggled to an 0-1 record and 6.75 ERA with 13 strikeouts over 12 innings of work. On 11 September, Scott was designated for assignment following Craig Stammen's activation from the injured list.
Philadelphia Phillies
On 14 September 2022, Scott was claimed off waivers by the Philadelphia Phillies. In four appearances for the Triple–A Lehigh Valley IronPigs, Scott struggled to a 15.00 ERA with four strikeouts in three innings of work. He was designated for assignment on 16 December, after the Phillies signed Taijuan Walker. Scott cleared waivers and was sent outright to Triple–A on 23 December; however, he declined the assignment and became a free agent.
Los Angeles Dodgers
On 7 January 2023, Scott signed a minor-league contract with the Los Angeles Dodgers. He began the season with Triple-A Oklahoma City, allowing only two earned runs in innings before he was called up to the majors on 22 May. He pitched six innings across six games for the Dodgers, posting a 9.00 ERA before he was designated for assignment on 17 June.
Boston Red Sox
On 22 June 2023, Scott was traded to the Boston Red Sox in exchange for cash considerations; he was assigned to the Triple-A Worcester Red Sox. On 4 July, Scott was added to Boston's active roster. In four games for Boston, Scott pitched innings and surrendered three runs (two earned) on six hits and four walks with two strikeouts. He was designated for assignment on 16 July.
Oakland Athletics
On 19 July 2023, Scott was claimed off waivers by the Oakland Athletics. In 8 games for Oakland, he registered a 3.38 ERA with 7 strikeouts in 8 innings of work. Following the season on 6 November, Scott was removed from the 40–man roster and sent outright to the Triple–A Las Vegas Aviators. He elected free agency the same day.
Houston Astros
On 12 December 2023, Scott signed a minor-league contract with the Houston Astros. On 28 March 2024, Scott had his contract selected after making Houston's Opening Day roster. Scott earned his first major league win on 2 May when he tossed scoreless innings versus the Cleveland Guardians to support an 8–2 final. The Astros placed Scott on the 15-day injured list on 21 September due to a thoracic spine strain. Through the point of the roster move, Scott had made the third-most appearances for the Astros and had produced a 2.23 ERA, 71 strikeouts, a 25.2% strikeout rate, and a 3.5% barrel rate over his innings. He did struggle with walks, however, at 12.4%.
Scott made 17 appearances for the Astros in 2025, posting a 1–2 record and 5.40 ERA with 16 strikeouts across innings pitched. Scott was designated for assignment by the Astros on 14 May 2025. On 21 May, Scott cleared waivers and elected free agency, rejecting the outright assignment to the Triple-A Sugar Land Space Cowboys.
Arizona Diamondbacks
/ref> He made three scoreless appearances for the Triple-A Reno Aces before being added to Arizona's active roster on 10 June. In nine appearances for Arizona, Scott struggled to a 9.00 ERA with seven strikeouts over nine innings of work. On 28 June, Scott was designated for assignment by the Diamondbacks. He elected free agency after clearing waivers on 1 July.
Houston Astros (second stint)
On 4 July 2025, Scott signed a minor league contract with the Houston Astros.
External links